K9 Advantix II Review & Comparison in 2021

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The phrase “tick season” and “flea season” varies depending on where you live. Summer and fall are peak tick seasons in general; but, since ticks prefer warmer climates, people that live in areas that are warm all year are at greater risk.

Tick bites, flea bites, flea-borne and tickborne diseases are very dangerous to dogs. Many tick-borne and flea-borne diseases that dogs can acquire do not have vaccines, and they do not prevent dogs from carrying ticks and fleas into your home. Tick and flea prevention products should be used on your dog for these purposes.

Here, we’ll review the K9 Advantix II to see if it is really effective so, let’s go!

K9 Advantix II Review

The K9 Advantix II is one of the most widely used flea and tick repellents on the market. Its success stems from the fact that it really works, and dogs rarely respond when it is added to their skin.

Most people who use this product are happily shocked by how easy it is to use and how effective it is at killing ticks.

Features of the K9 Advantix II


The K9 Advantix II has various options to choose form depending on what type and weight your dog is.

This vet-recommended flea and tick will help control infestation of small dogs to large dogs. The only thing you need to do is to buy the right one for your dog.

Easy to Apply

A tiny pipette holds the substance, which is used for the application. To allow the treatment to seep through the skin, the dog’s fur along its spine just needs to be parted and kept close to one hand before applying.

However, if your dog moves around a lot, you might have trouble applying the formula equally. Some users have claimed that their dog’s skin is a bit irritated, especially small breeds of dogs, so pay attention to the amount of chemical you’re giving your dog and make sure you’ve bought the correct solution for their weight.

The K9 Advantix II comes in convenient, one-month applications of topical solution. Simply apply once a month all year-round for effective protection against fleas and ticks.

Safe and Hypoallergenic

This great formula is developed by Bayer, which has established itself as one of the world’s most prestigious pharmaceutical firms. As a result, this flea and tick drug is high-quality and brand-name, so customers can be assured that their pet’s wellbeing is in the best possible hands when they purchase it. It will be perfect as long as your dog isn’t too light for the formula you’ve bought.

However, take note that this specific solution is not intended for cats, and exposing a cat to it could result in serious damage. This product can be kept out of the hands of children because it can be dangerous if swallowed. So, make sure to have precautions always when dealing with this.

Great Formula

The active ingredients in K9 Advantix II for dogs are imidacloprid, permethrin, and pyriproxyfen. It is used to help your dog’s skin to remove and repel fleas, ticks, and mosquitoes, repel biting flies, and kill lice.

Fast and Effective

The reason why this product performs well because it has satisfied, long-term buyers and a thriving industry. Your dog should cease itching after 12 hours since both ticks and fleas should have died by then.

There are numerous online reviews from satisfied consumers that say that this formula continues to work against fleas and ticks. The brand has been around for a long time and aims to improve its quality year after year.

Another good thing about the K9 Advantix II is that it also kills and repels mosquitoes, a benefit not found in many other flea and tick products.

Overall Protection

The active ingredients will penetrate through your dog’s skin and provide protection all across his body. Since this treatment is applied to the outer layers of your dog’s skin, it never reaches the bloodstream. The formula eradicates ticks and fleas in all stages of their life cycle on your dog and then serves as a barrier against emerging fleas and ticks. If there are flea larvae or fully-grown fleas in your dog’s hair, this treatment will get rid of them quickly.

Advantix is a fantastic product. Advantix is completely effective even just after two days of use. Ticks will get on the dog within the first day or two, but they will not split the skin to eat. This formula is really safe and does not irritate the dog’s skin like other products available on the market.

  • Odorless formula
  • Hypoallergenic for dogs
  • Kills ticks fast
  • Can withstand harsh sunlight and water
  • A bit pricey
  • Can be less effective on heavily wounded areas

Advantix vs. Advantage

They are both effective against fleas, but that’s really where the similarities with effectiveness ends. K9 Advantix II has the added benefit of killing and repelling ticks and mosquitoes, whereas Advantage has no effect on these parasites at all.

Another thing is that Advantage has formulations that are certified for both dogs and cats, whereas Advantix is exclusively for dogs. Permethrin toxicity in cats is a frequent occurrence, particularly during the spring and summer months, when fleas are at their most bothersome. So make sure to choose Advantix if you have cats and dogs.

K9 Advantix II vs. Frontline Plus

If you are familiar with other brands, the Frontline is the well-known competitor of the K9Advantix. Let’s see what are their main differences when it comes to their product formulation.

First thing is that Frontline is available in a 3-month supply for almost half the price of a 6-month supply of K9 Advantix 2.

Frontline uses fipronil, while K9 Advantix II uses imidacloprid and permethrin. A research compared the effectiveness of imidacloprid and fipronil, finding that both were successful, but imidacloprid had a faster kill rate than fipronil.

Although being a little more costly, we’ve heard from a number of people who have switched from Frontline to Advantix and are seeing better performance. This makes sense because Advantix’s ingredients have been shown to be significantly more reliable.


Ticks and fleas are huge problems and can also affect the health of your dogs. However, tick and flea prevention products are readily available in the market to control and win over tick and flea infestation. You just need to look up for what is the best methods fully exterminate them and let your dogs have their happy life.

I hope this article helped you dealing with ticks and fleas on your dogs and make sure to check our other articles if you enjoyed this!

1 Comment

  1. Kelly Alexander

    Frontline Plus Vs. K9 Advantix II.. Please read our true experience.. it may help you decide.
    Frontline Plus was a nightmare product. I’ve never seen anything like it. I gave this to our 2 yo Shi-Chi and it was almost like the infestation got worse! I am assuming because we assumed it would work. We continued to treat the home, bedding, yard etc. I guess we lost sight of treating the dog with this assumption. So the fleas got worse on her. After almost a month of this craziness. I did the internet search on Frontline plus and found we were not alone! According to other dog owners. Due to Frontlines popularity and excessive use. Fleas have become resistant to the main ingredients in Frontline Plus. It has been used with great success in the PAST. So we resorted to exposing my dog to another chemical treatment K9 Advantix II.
    Indeed it worked! My little buddy is sleeping comfortably again. Within the first 24hrs I’d say.. the fleas are gone. I stumbled on this article and thought it would be a great place to share. If anyone is hesitating between the two. Spend the extra for Advantix. Your best friend will thank you!!

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